Desire generated by office worker joining establishment, putting leader off (10)
I believe the answer is:
temptation
'desire' is the definition.
(I know that temptation is a type of desire)
'office worker joining establishment putting leader off' is the wordplay.
'office worker' becomes 'temp' (I've seen this in another clue).
'joining' says to put letters next to each other.
'establishment' becomes 'station'.
'putting leader off' means to remove the first letter.
'station' with its initial letter taken off is 'tation'.
'temp'+'tation'='TEMPTATION'
'generated by' acts as a link.
(Other definitions for temptation that I've seen before include "seduction" , "Enticement" , "Enticing desire to do something" .)