Despite appearances, it doesn't mean 'from' (4)
I believe the answer is:
unto
'despite appearances' is the definition.
I know nothing about this answer so I can't tell whether this works.
'it doesn't mean from' is the wordplay.
I cannot quite see how this works, but
'it' could be 't' (abbreviation. e.g. in 'tis) and 't' is found in the answer.
'from' could be 'o' (I've seen this in other clues) and 'o' is found in the answer.
The remaining letters 'un' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for unto that I've seen before include "'Do ... others, etc.'" , "Biblical preposition, the archaic 'to'" , "To (obs.)" , "Heading for" , "Archaic form of to" .)