Destine for failure
I believe the answer is:
doom
'destine for failure' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for doom that I've seen before include "Fate; condemn to death" , "Fate; ruin" , "Mood of death or ruin" , "Condemn to certain destruction" , "Sentence" .)