Destined to give party new mode (6)
I believe the answer is:
doomed
'destined' is the definition.
('doom' can be a synonym of 'destine')
'give party new mode' is the wordplay.
'give' means one lot of letters go next to another.
'party' becomes 'do' (do is a kind of party).
'new' is an anagram indicator.
'mode' with letters rearranged gives 'omed'.
'do' put next to 'omed' is 'DOOMED'.
'to' is the link.
(Other definitions for doomed that I've seen before include "Under sentence" , "Fated" , "Greek god" , "Destined to a grim fate, perhaps hell (6)" , "Consigned or sentenced to hell" .)