Destiny of St Mike, perhaps (6)
I believe the answer is:
kismet
'destiny' is the definition.
(kismet is a kind of destiny)
'st mike perhaps' is the wordplay.
'perhaps' is an anagram indicator.
'st'+'mike'='stmike'
'stmike' with letters rearranged gives 'KISMET'.
'of' is the link.
(Other definitions for kismet that I've seen before include "Fate - 1953 musical" , "Broadway musical" , "fortune" , "Destiny; 50s musical" , "Will of Allah" .)