Destiny sees detective back in the south of France (10)
I believe the answer is:
providence
'destiny' is the definition.
(thesaurus)
'detective back in the south of france' is the wordplay.
'detective' becomes 'di' (Detective Inspector abbreviation).
'back' says the letters should be written backwards.
'in the' means one lot of letters goes inside another.
'south of france' becomes 'provence'.
'di' back-to-front is 'id'.
'id' inserted into 'provence' is 'PROVIDENCE'.
'sees' acts as a link.
(Other definitions for providence that I've seen before include "US state capital" , "fortune" , "tender care" .)