Destroy; disable (5)
I believe the answer is:
wreck
This clue is a double definition.
'destroy' is the first definition.
(I know that wreck is a more specific form of the action destroy)
'disable' is the second definition.
(thesaurus)
(Other definitions for wreck that I've seen before include "Completely spoil" , "Utterly destroy" , "Devastate" , "Destroy, ruin" , "Demolish; sunken ship" .)