Determination of women suffering (4)
I believe the answer is:
will
'determination' is the definition.
(thesaurus)
'women suffering' is the wordplay.
'women' becomes 'w'.
'suffering' becomes 'ill'.
'w'+'ill'='WILL'
'of' acts as a link.
(Other definitions for will that I've seen before include "- And Grace, TV series" , "A traditional question from the floor?" , "Testament or determination" , "Resolve - testament" , "Determination; 22 author" .)