Dextrous, skilful (6)
I believe the answer is:
adroit
I believe this clue is a double definition.
'dextrous' is the first definition.
(similar in meaning)
'skilful' is the second definition.
(adroit can mean skilful or masterful)
(Other definitions for adroit that I've seen before include "Quick and clever in action or thought" , "Skilful or ingenious" , "Deft and proficient" , "Skilful, expert" , "Dexterous, artful" .)