Dictator from south in bus station (6)
I believe the answer is:
despot
'dictator' is the definition.
(despot is a kind of dictator)
'south in bus station' is the wordplay.
'south' becomes 'S' (synonyms).
'in' indicates putting letters inside.
'bus station' becomes 'depot' (I've seen this before).
's' put into 'depot' is 'DESPOT'.
'from' acts as a link.
(Other definitions for despot that I've seen before include "Posted (anag)" , "Cruel absolute ruler" , "Person with more than enough power" , "Cruel and oppressive dictator" , "One exploiting rule" .)