Didn't save an animal shelter in the street (5)
I believe the answer is:
spent
'didn't save' is the definition.
(I've seen this in another clue)
'an animal shelter in the street' is the wordplay.
'an animal' becomes 'pen' (pen is a kind of animal).
'shelter in' is an insertion indicator.
'the street' becomes 'st' (abbreviation).
'pen' put within 'st' is 'SPENT'.
(Other definitions for spent that I've seen before include "Exhausted, having paid money?" , "Worn out having paid out money." , "Expended" , "Worn out, having laid out money" , "Worn Out, exhausted" .)