Difficulty, strife (7)
I believe the answer is:
trouble
This clue is a double definition.
'difficulty' is the first definition.
(trouble can mean a difficult situation)
'strife' is the second definition.
(I've seen this before)
(Other definitions for trouble that I've seen before include "Jam" , "Worry - predicament" , "Difficulty; public disorder" , "Cause distress to; unrest" , "Effort - (cause of) worry" .)