Diffuse cloud of particles and gases visible either as a hazy patch of light or an irregular dark region (6)

I believe the answer is:

nebula

(Other definitions for nebula that I've seen before include "A little cloudy" , "Diffuse cloud of particles and gas in space" , "Unable (anag)" , "Hazy light; a slight cloudiness" , "Unable to find patch in the sky" .)

I've seen this clue in The Independent.

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