Direct the course of (5)
I believe the answer is:
steer
'direct the course of' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for steer that I've seen before include "Pilot a boat in desired direction" , "farm animal" , "Direct; bullock" , "member of herd" , "Guide (eg, a ship)" .)