Directions for replacement
I believe the answer is:
new
'replacement' is the definition.
'directions for' is the wordplay.
'directions' becomes 'ne' (I've seen this in other clues).
'for' becomes 'w' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'ne'+'w'='NEW'
Can you help me to learn more?
(Other definitions for new that I've seen before include "Fresh, unused" , "Unfamiliar, restored" , "Unused or novel" , "Seen for the first time" , "Original" .)