Disagree with (6)
'disagree with' is the definition.
(thesaurus)
This is the entire clue.
(Other definitions for oppose that I've seen before include "Resist; play against" , "Compete with" , "Take stand against, resist" , "Act against" , "Resist; disapprove of" .)
'disagree with' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for take issue that I've seen before include "Disagree" , "dispute" , "Object" , "Don't agree" , "challenge" .)