Disagreeably negative start to talks (3)
I believe the answer is:
not
'disagreeably' is the definition.
Both the answer and definition are adverbs. Perhaps there's an association between them I don't understand?
'negative start to talks' is the wordplay.
'negative' becomes 'no' (no is a kind of negative).
'start to' indicates taking the first letters.
The initial letter of 'talks' is 't'.
'no'+'t'='NOT'
Can you help me to learn more?
(Other definitions for not that I've seen before include "Negatory word" , "Word of denial" , "logically, operation needed" , "Having close-cut hair" , "Word of negation" .)