Disaster, calamity (11)
I believe the answer is:
catastrophe
I believe this clue is a double definition.
'disaster' is the first definition.
(synonyms)
'calamity' is the second definition.
(synonyms)
(Other definitions for catastrophe that I've seen before include "Event causing much damage" , "Sudden disaster" , "Terrible event" , "Event causing great damage" , "Event causing great suffering" .)