Discharge from the chamber, say (5)
I believe the answer is:
rheum
'discharge' is the definition.
(I know that rheum is a type of discharge)
'chamber say' is the wordplay.
'chamber' becomes 'room' (I've seen this before).
'say' indicates a 'sounds like' (homophone) clue.
'room' is a homophone of 'RHEUM'.
'from the' is the link.
(Other definitions for rheum that I've seen before include "that's rather snotty?" , "Flowing water" , "Poetic tears" , "Watery discharge from eyes or nose" , "Watery stuff" .)