Discomfort or apprehension (6)
I believe the answer is:
unease
I believe this is a double definition.
'discomfort' is the first definition.
(unease is a kind of discomfort)
'apprehension' is the second definition.
(I've seen this before)
(Other definitions for unease that I've seen before include "Disquiet" , "Anxiety, discontent" , "State of anxiety" , "State of worry and lack of confidence" , "Discomfort or apprehension" .)