Discontent on the rise in Shanghai, unnervingly (5)
I believe the answer is:
ennui
'discontent' is the definition.
(ennui is a kind of discontent)
'the rise in shanghai unnervingly' is the wordplay.
'the rise' shows that the letters should be reversed in order.
'in' indicates a hidden word.
'iunne' is hidden in the letters of 'shanghai unnervingly'.
'iunne' in reverse letter order is 'ENNUI'.
'on' is the link.
(Other definitions for ennui that I've seen before include "Boredom, tedium" , "tiredness" , "Listless feeling" , "depression" , "Weariness with life" .)