Discrimination when manipulating images (6)
I believe the answer is:
ageism
'discrimination' is the definition.
(ageism is a kind of discrimination)
'manipulating images' is the wordplay.
'manipulating' is an anagram indicator (I've seen this in other clues).
'images' is an anagram of 'AGEISM'.
'when' acts as a link.
(Other definitions for ageism that I've seen before include "Images about prejudice against old people" , "Form of discrimination" , "Discrimination on grounds of age" , "Bad attitude to the grey" , "Prejudice or bias against old people" .)