Discussed lines of enquiry in city (5)
I believe the answer is:
leeds
'in city' is the definition.
(I've seen this before)
'discussed lines of enquiry' is the wordplay.
'discussed' shows a homophone (sound like).
'lines' becomes 'll' (two abbreviations for line).
'of enquiry' becomes 'eds' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'll' sounds like 'le'.
'le'+'eds'='LEEDS'
Can you help me to learn more?
(Other definitions for leeds that I've seen before include "Championship team" , "Industrial city of northern England" , "City of northern England - castle of southern England" , "Yorkshire city - Kent castle" , "22 [FA CUP] runners-up" .)