Disesteem; rudeness (10)
I believe the answer is:
disrespect
This clue is a double definition.
'disesteem' is the first definition.
(I know that disesteem can be written as disrespect)
'rudeness' is the second definition.
(I know that rudeness can be written as disrespect)
(Other definitions for disrespect that I've seen before include "Discourtesy" , "Lack of reverence" , "Rudeness" , "Contempt" , "Lack of courtesy" .)