Dislike neighbourhood being restricted, with east in disarray (8)
I believe the answer is:
distaste
'dislike' is the definition.
(I know that distaste is a type of dislike)
'neighbourhood being restricted with east in disarray' is the wordplay.
I cannot really understand how this works, but
an anagram of 'east' is 'aste' which is present in the answer.
This may be the basis of the clue (or it may be nonsense).
(Other definitions for distaste that I've seen before include "Feeling of dislike or aversion" , "Not liking" , "Adverse reaction" , "mild revulsion" , "Negative feeling" .)