Dislike tangling thread (6)
I believe the answer is:
hatred
'dislike' is the definition.
(I've seen this before)
'tangling thread' is the wordplay.
'tangling' is an anagram indicator (I've seen 'tangled' mean this).
'thread' with letters rearranged gives 'HATRED'.
(Other definitions for hatred that I've seen before include "Intense dislike" , "Great dislike" , "'Loathing, enmity (6)'" , "Extreme dislike and enmity" , "Dearth (anag)" .)