Disorder upsetting grandee (7)
I believe the answer is:
derange
'disorder' is the definition.
(synonyms)
'upsetting grandee' is the wordplay.
'upsetting' is an anagram indicator.
'grandee' anagrammed gives 'DERANGE'.
(Other definitions for derange that I've seen before include "Drive mad" , "Upset" , "Throw into disorder" , "Make mad" , "Put into confusion" .)