Disorganised people go off them (5)
I believe the answer is:
rails
I'm afraid I can't even guess how this answer relates to the clue.
Can you help me to learn more?
(Other definitions for rails that I've seen before include "Metal bars of a barrier" , "Barriers of horizontal bars and supports" , "Wading birds - dysfunctional person has come off them" , "For trains" , "Makes a protest" .)