Disregard one note and not another (6)
I believe the answer is:
ignore
'disregard' is the definition.
(I know that disregard can be written as ignore)
'one note and not another' is the wordplay.
'one' becomes 'i' (Roman numeral).
'note' becomes 'g' (musical note).
'and' says to put letters next to each other.
'not another' becomes 'nore' (I can't explain this - if you can you should give a lot more credence to this answer).
'i'+'g'+'nore'='IGNORE'
Can you help me to learn more?
(Other definitions for ignore that I've seen before include "Fail to consider" , "Intentionally disregard" , "Pass over" , "Deliberately overlook" , "Fail to observe" .)