Disrupt drunken teen lust (8)
I believe the answer is:
unsettle
'disrupt' is the definition.
(thesaurus)
'drunken teen lust' is the wordplay.
'drunken' is an anagram indicator.
'teen'+'lust'='teenlust'
'teenlust' anagrammed gives 'UNSETTLE'.
(Other definitions for unsettle that I've seen before include "'Disturb, unnerve (8)'" , "Make someone ill at ease" , "'Disturb, make uneasy (8)'" , "Make uneasy, disturb the calm of" , "Disrupt" .)