Disruptive Latinos cunningly infiltrated by spies (10)
I believe the answer is:
antisocial
'disruptive' is the definition.
(disruptive to society)
'latinos cunningly infiltrated by spies' is the wordplay.
'cunningly' is an anagram indicator (a cunning or tricky form of the letters).
'infiltrated by' is an insertion indicator.
'spies' becomes 'CIA' (Central Intelligence Agency).
'latinos' anagrammed gives 'antisol'.
'antisol' going around 'cia' is 'ANTISOCIAL'.
(Other definitions for antisocial that I've seen before include "Reluctant to mix" , "Not getting on with others" , "Avoiding the company of others" , "Disinclined to mix" , "Disruptive to the community" .)