Distresses (6)
I believe the answer is:
upsets
'distresses' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for upsets that I've seen before include "Disapppointments" , "Disturbs, distresses" , "Makes unhappy or worried" , "Reversals" , "Disturbs or knocks over" .)