Do drugs after American working girl gets home? (5)
I believe the answer is:
house
'home?' is the definition.
(I know that home can be written as house)
'do drugs after american working girl' is the wordplay.
'do drugs' becomes 'use' (as in using drugs).
'after' is a charade indicator (letters next to each other).
'american working girl' becomes 'ho' (US term for a prostitute).
'use' put after 'ho' is 'HOUSE'.
'gets' is the link.
(Other definitions for house that I've seen before include "Home building" , "Residence; legislative meeting-place" , "Accommodate" , "Building for dwelling in" , "See 18" .)