Do not acknowledge daughter is initially offhand with neighbours (6)
I believe the answer is:
disown
'do not acknowledge' is the definition.
I can't tell whether this defines the answer.
'daughter is initially offhand with neighbours' is the wordplay.
'daughter' becomes 'd' (genealogical abbreviation).
'initially' says to take the initial letters.
The initial letters of 'offhand with neighbours' is 'own'.
'd'+'is'+'own'='DISOWN'
Can you help me to learn more?
(Other definitions for disown that I've seen before include "Repudiate - disinherit" , "Refuse to be associated with (something/someone)" , "Refuse responsibility for" , "Refuse to have anything to do with" , "Reject all connection with, refuse to acknowledge" .)