Doctor amused scary female (6)
I believe the answer is:
medusa
'scary female' is the definition.
'medusa' can be an answer for 'female' (I have seen 'Hideous female' mean 'medusa' so perhaps 'female' could also mean 'medusa'). I am not sure about the 'scary' bit.
'doctor amused' is the wordplay.
'doctor' indicates anagramming the letters.
'amused' anagrammed gives 'MEDUSA'.
Can you help me to learn more?
(Other definitions for medusa that I've seen before include "Mythological gorgon" , "Mythical woman transformed into a Gorgon" , "all her visitors got stoned" , "One of three sisters with snakes for hair" , "Mythical woman with snakes for hair" .)