Dog set sail around UK! (6)
I believe the answer is:
saluki
'dog' is the definition.
(I've seen this before)
'set sail around uk' is the wordplay.
'set' indicates anagramming the letters (instruction to set the letters).
'around' is an insertion indicator.
'sail' with letters rearranged gives 'sali'.
'sali' going around 'uk' is 'SALUKI'.
(Other definitions for saluki that I've seen before include "Tall breed of hound" , "it's silky and has bark" , "Tall hunting dog (like a greyhound) from Egypt and south-western Asia" , "Persian greyhound" , "Tall slender dog" .)