Doing one's best to be a nuisance (6)
I believe the answer is:
trying
'doing' is the definition.
The definition and answer can be both related to bodily activities as well as being present participle verbs.
Perhaps they are linked in a way I don't understand?
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for trying that I've seen before include "Attempting or irritating" , "Working in a court can be" , "What could be witnessed in court" , "Attempting or stretching patience to the limit" , "undertaking" .)