Doing one's best to be irksome (6)
I believe the answer is:
trying
'to be irksome' is the definition.
(I've seen this in another clue)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for trying that I've seen before include "work on bench" , "Attempting or irritating" , "Exasperating" , "Bothersome" , "Tiresome" .)