Domains in which actual manuscript is found (6)
I believe the answer is:
realms
'domains' is the definition.
(I know this)
'actual manuscript is found' is the wordplay.
I cannot really see how this works, but
'actual' could be 'real' (similar in meaning) and 'real' is found in the answer.
'manuscript' could be 'ms' (abbreviation for manuscript) and 'ms' is present in the answer.
No letters remain.
This explanation may well be incorrect...
'in which' acts as a link.
Can you help me to learn more?
(Other definitions for realms that I've seen before include "Fields of activity or interest - sound monarchical" , "Kingdoms, domains" , "Kingdoms, or fields of activity" , "Domains - provinces" , "Kingdoms, or fields of interest" .)