Domesticated and possibly mated (5)
I believe the answer is:
tamed
'domesticated' is the definition.
(similar in meaning)
'possibly mated' is the wordplay.
'possibly' indicates an anagram.
'mated' anagrammed gives 'TAMED'.
'and' is the link.
(Other definitions for tamed that I've seen before include "Of animals, domesticated" , "now behaving himself?" , "Domesticated or subdued" , "Reined" .)