Domino effect of a car on thin ice skidding (5,8)
I believe the answer is:
chain reaction
'domino effect' is the definition.
(I've seen this before)
'a car on thin ice skidding' is the wordplay.
'skidding' is an anagram indicator.
'a'+'car'+'on'+'thin'+'ice'='acaronthinice'
'acaronthinice' with letters rearranged gives 'CHAIN REACTION'.
'of' is the link.
(Other definitions for chain reaction that I've seen before include "Series of linked events" , "that could get out of control" , "Sequence" , "Diana Ross song" , "inevitably following flush?" .)