Done with English politician, has one’s excessive level of stress (12)
I believe the answer is:
overemphasis
'excessive level of stress' is the definition.
'overemphasis' can be an answer for 'stress' (I have seen 'Excessive stress ' mean 'overemphasis' so perhaps 'stress' could also mean 'overemphasis'). I'm unsure of the 'excessive level of' bit.
'done with english politician has one's' is the wordplay.
'done with' becomes 'over' (similar in meaning as in 'over and done with').
'english' becomes 'E' (abbreviation).
'politician' becomes 'MP' (Member of Parliament).
'one's' becomes 'i's' (Roman numeral).
'over'+'e'+'mp'+'has'+'is'='OVEREMPHASIS'
Can you help me to learn more?
(Other definitions for overemphasis that I've seen before include "Too much stress" , "Excessive stress" , "Excessive underlining" .)