Don't go to s-sleep (4)
I believe the answer is:
skip
'don't go to' is the definition.
(I've seen this in another clue)
's-sleep' is the wordplay.
'sleep' becomes 'kip' (synonyms).
's'+'kip'='SKIP'
(Other definitions for skip that I've seen before include "Omit; fail to attend" , "leave something out" , "Avoid" , "Omit - refuse container" , "Jump, pass over" .)