Doom affected temper (4)
I believe the answer is:
mood
'temper' is the definition.
('mood' can be a synonym of 'temper')
'doom affected' is the wordplay.
'affected' indicates anagramming the letters.
'doom' with letters rearranged gives 'MOOD'.
(Other definitions for mood that I've seen before include "Disposition" , "Depression" , "Frame of mind" , "Bad feeling" , "Temporary state of mind" .)