Dotty West makes casserole (4)
I believe the answer is:
stew
'casserole' is the definition.
(casserole is a type of stew)
'dotty west' is the wordplay.
'dotty' is an anagram indicator (a mad or 'dotty' version of the letters).
'west' anagrammed gives 'STEW'.
'makes' is the link.
(Other definitions for stew that I've seen before include "are nervous" , "Go West for this dish" , "Cook (in one's own juices?)" , "tart" , "Meat and veg dish" .)