Downhearted, dejected (12)
I believe the answer is:
disconsolate
I believe this clue is a double definition.
'downhearted' is the first definition.
(thesaurus)
'dejected' is the second definition.
(I've seen this before)
(Other definitions for disconsolate that I've seen before include "Stuck with the blues" , "Sad; beyond comfort" , "Low in spirits" , "Melancholy" , "Unhappy and impossible to comfort" .)