Dr No book reworked opening device (8)
I believe the answer is:
doorknob
'opening device' is the definition.
(doorknobs open doors)
'dr no book reworked' is the wordplay.
'reworked' indicates an anagram.
'dr'+'no'+'book'='drnobook'
'drnobook' anagrammed gives 'DOORKNOB'.
(Other definitions for doorknob that I've seen before include "Turn it to gain entrance" , "Handle for portal" , "Indian antelope; Hun gyal (anag.)" , "Latch opener" , "Round handle" .)