Dramatic act hit with Lear indisposed (10)
I believe the answer is:
theatrical
'dramatic' is the definition.
(thesaurus)
'act hit with lear indisposed' is the wordplay.
'with' means one lot of letters go next to another.
'indisposed' indicates an anagram.
'act'+'hit'+'lear'='acthitlear'
'acthitlear' with letters rearranged gives 'THEATRICAL'.
(Other definitions for theatrical that I've seen before include "overdramatic" , "Stagy" , "Actor" , "Excessively dramatic" , "Showbiz" .)