Dramatist in predicament is unusually wary (10)
I believe the answer is:
playwright
'dramatist' is the definition.
('playwright' can be a synonym of 'dramatist')
'in predicament is unusually wary' is the wordplay.
'in' means one lot of letters goes inside another.
'predicament' becomes 'plight' ('plight' can be a synonym of 'predicament').
'is unusually' indicates anagramming the letters.
'wary' is an anagram of 'aywr'.
'plight' going around 'aywr' is 'PLAYWRIGHT'.
(Other definitions for playwright that I've seen before include "Author of dramas" , "Coward, possibly" , "Will, say" , "16 dn of dramas" , "Coward, for one" .)