Dreadfully disables the securely settled (11)
I believe the answer is:
established
'securely settled' is the definition.
'established' can be an answer for 'settled' (similar in meaning). I am not certain of the 'securely' bit.
'dreadfully disables the' is the wordplay.
'dreadfully' indicates anagramming the letters (a dreadful spelling).
'disables'+'the'='disablesthe'
'disablesthe' with letters rearranged gives 'ESTABLISHED'.
Can you help me to learn more?
(Other definitions for established that I've seen before include "just like the church!" , "Settled and recognised" , "He is baldest (anag.)" , "Set up; settled" , "Long-standing" .)